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NOTICE: The PRO ID format has changed from PRO: to PR: (e.g. PRO:000000563 is now PR:000000563).
HOME / Protein Ontology

(NIH grants 1R01GM080646-01, 3R01GM080646-04S1, 3R01GM080646-04S2, 5R01GM080646-05)
PRO provides an ontological representation of protein-related entities by explicitly defining them and showing the relationships between them. Each PRO term represents a distinct class of entities (including specific modified forms, orthologous isoforms, and protein complexes) ranging from the taxon-neutral to the taxon-specific (e.g. the constitutive active form of rho-associated protein kinase 1 isoform 1 resulting from proteolytic cleavage is described in PR:000000563, whereas the unmodified form is defined by PR:000002529). Current release: 38.0.
PRO Wiki
PRO tutorial
PRO Paper
PRO Statistics
Browse PRO

Example: methylated (sample output)
Retrieve a PRO entry (enter a PRO ID):

Example: PR:000000563 (sample output)
Search PRO (enter text or ID):

Example: smad (sample output)
Annotation: RACE-PRO PRO tracker
PRO encompasses three sub-ontologies: proteins based on evolutionary relatedness (ProEvo); protein forms produced from a given gene locus (ProForm); and protein-containing complexes (ProComp).
(Explanation of the figure)

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